A possible concise summary is:
The video is about a challenge to beat Skyrim with every disease in the game. The narrator explains the effects of each disease and how he contracted them. He also describes his build, strategy, and equipment choices. He manages to overcome the debuffs and complete the main quest with the help of some shouts and allies. He concludes that the challenge was more difficult in the beginning, but became easier as he leveled up.
Here are the key facts extracted from the text:
1. In Skyrim, death is usually due to combat or gravity.
2. The protagonist does not die from diseases but receives debuffs from wildlife.
3. The challenge is to play Skyrim with every disease.
4. The player character is an Argonian with a 50% resistance to disease.
5. The player avoids combat until contracting every disease.
6. Lycanthropy cures all other diseases, so it's not contracted for this run.
7. Vampirism is considered for the run, with details to follow.
8. The player character starts by following Hadvar during the opening sequence.
9. Standing stones are not used in this playthrough.
10. The player sells gear in Riverwood before seeking out wolves to contract Rockjoint.
11. Contracting diseases proves difficult due to the Argonian's resistance.
12. Plan B involves using a carriage to Riften and finding Redwater Den for diseases.
13. Redwater Den is a secret drug den run by vampires.
14. Drinking from the Bloodspring at Redwater Den inflicts all diseases on the player character.
15. A new disease called Droops was added in the Dragonborn DLC and is contracted from ash hoppers in Solstheim.
16. The player character uses two-handed weapons as the main skill despite debuffs.
17. Sanguinare Vampiris reduces max health by 25 and progresses to vampirism.
18. Ataxia affects pickpocketing and lockpicking abilities.
19. Brain Rot reduces magicka by 25 points.
20. Witbane slows magicka regeneration by 50%.
21. Bone Break Fever reduces max stamina by 25 points.
22. Rattles slows stamina recovery rate.
23. Droops lowers one-handed and two-handed weapon damage by 15%.
24. Rockjoint decreases melee weapon effectiveness by 25%.
25. The player character focuses on archery and sneak skills due to debuffs.
Please let me know if you need more details or further assistance!