Here is a concise summary of the provided text about Fluoxetine (e.g., Prozac):
**Overview**
* Fluoxetine is a widely used antidepressant and selective serotonin reuptake inhibitor (SSRI)
* Used to treat depression, anxiety disorders (e.g., panic syndrome), bulimia, and menstrual tension symptoms
**Key Precautions and Considerations**
* **Dosage**: 20-80 mg/day, adjusted based on individual metabolism
* **Administration**: Can be taken at any time, but recommended in the morning; take with food to minimize stomach irritation
* **Onset of Action**: 2-4 weeks to start, up to 6 weeks for full effect
* **Common Side Effects** (usually transient, especially in the first two weeks):
+ Gastrointestinal symptoms (diarrhea, nausea)
+ Dizziness
+ Increased anxiety/irritability (initially)
+ Changes in appetite (common, but weight loss is not guaranteed)
+ Potential sexual side effects (less common)
**Special Considerations**
* **Elderly/Children/Adolescents**: Can be used, but with lower initial doses
* **Pregnancy/Lactation**: Considered safe, but decision should be made jointly with healthcare providers
* **Drug Interactions**: Be cautious with anticoagulants, certain psychiatric medications, and potential effects on diabetes management
* **Withdrawal**: Should not be done abruptly to avoid unpleasant symptoms
**General Reminder**
* Always use medication under the supervision of a healthcare professional (psychiatrist, neurologist, or primary care physician).
Here are the key facts extracted from the text, numbered and in short sentences, excluding opinions:
**Medication Overview**
1. Fluoxetine is a widely used antidepressant medication.
2. It was the first selective serotonin reuptake inhibitor (SSRI) launched.
3. Brand names include Prozac, Fluxene, Verotina, Daforin, and Psiquial Rapida.
**Metabolism and Administration**
4. Fluoxetine is metabolized in the liver without overloading it.
5. Available forms: drops, tablets, capsules, D10, and D20 MG.
6. Therapeutic dosage ranges from 20 MG (minimum) to 80 MG (maximum for most people).
7. Dosage may vary based on individual metabolism.
8. No interaction between Fluoxetine and food, but recommended to take after eating.
9. Typically recommended to take in the morning, especially for the elderly.
**Dosage and Forgetting a Dose**
10. Initial prescribed dose for the elderly is usually low (10-20 MG).
11. If a dose is forgotten, take it as soon as remembered and restart the schedule the next day.
**Half-Life and Elimination**
12. Fluoxetine's half-life is 4 to 6 days, but complete elimination takes 4 to 16 days.
**Common Effects and Side Effects**
13. Therapeutic effects typically start within 2 to 4 weeks, with full action in up to 6 weeks.
14. Common adaptation effects in the first two weeks include gastrointestinal symptoms (diarrhea, nausea).
15. May cause dizziness, increased anxiety, and insomnia initially.
16. Can affect appetite, leading to decreased appetite in some patients (about one-fifth).
17. Appetite effects usually lessen after the first three months.
18. May influence sexual aspects (delayed orgasm, difficulty with erection, decreased libido), though less common.
**Special Populations**
19. Can be used in adults, the elderly, children, and adolescents.
20. Elderly and children may require smaller, more gradual doses.
21. Contraindicated in patients using certain psychiatric medications (e.g., Parnate, Aurorix); requires a 14-day wait after stopping those medications.
22. Caution advised with anticoagulant medications and potential influence on diabetes values.
**Pregnancy and Lactation**
23. Considered safe for lactating and pregnant women, but decision must be made jointly with the patient, psychiatrist, and obstetrician.
**Withdrawal**
24. Withdrawing from Fluoxetine should not be done abruptly to avoid unpleasant symptoms (dizziness, headache, sleep changes, irritability).
25. Gradual withdrawal is recommended to allow the body to adapt.