The story begins with a young boy who loses his parents in a car accident and is sent to live with his strict but loving Catholic grandmother in Alabama. The grandmother tries to cheer him up, but he remains sad until he meets a chubby boy named Bruno. However, Bruno is soon turned into a mouse by a group of witches who are staying at the same hotel.
The main antagonist, the great witch, plans to turn all the children in the world into mice and then have them exterminated by humans. The boy and his friends, including a talking mouse, come up with a plan to infiltrate the witches' soup with garlic, which repels them.
The plan works, and the witches are turned into monstrous rats. The great witch is defeated and devoured by her own cat. The grandmother and the children find a way to turn the witches into rats and then go on a mission to rid the world of witches. The story ends with the boy, now an old mouse, recruiting children to join him in his fight against witches.
The movie has a happy ending, with the grandmother and the children living happily together, and the boy living a long life as a mouse, thanks to the grandmother's care.
1. The film begins with a voice-over.
2. A man tells a story about his childhood through a PowerPoint presentation.
3. The man's parents died in a car accident when he was 8 years old.
4. The man's grandmother took him in after the accident.
5. The grandmother is a devout Catholic who also practices voodoo.
6. The grandmother tries to cheer up the man with music and cornbread.
7. The grandmother buys the man a mouse named Teixi.
8. The man and Teixi become close friends.
9. In a store, the man meets a strange and ugly woman who gives him a bad vibe.
10. The woman is a witch who hates children.
11. The grandmother tells the man that witches have secret societies and follow a leader called the Great Witch.
12. The Great Witch is the leader of the witches and is ruthless and lethal.
13. The grandmother and the man go to a hotel in Alabama to escape the witches.
14. The hotel is filled with wealthy and Caucasian children, and the grandmother believes they will be safe there.
15. However, the witches arrive at the hotel for a meeting.
16. The hotel manager is subtly racist but polite.
17. The Great Witch has a plan to eliminate all the children in the world.
18. The plan involves turning children into mice using a serum.
19. The witches will open candy stores to attract children and give them the serum.
20. A boy named Bruno is tricked into eating chocolate poisoned with the serum and turns into a mouse.
21. The man's mouse, Teixi, can talk and helps rescue Bruno.
22. However, the man is caught by the witches and turned into a mouse using the serum.
23. The man, Teixi, and Bruno escape through a ventilation duct.
24. The grandmother recognizes her grandson and helps him come up with a plan to defeat the witches.
25. The plan involves infiltrating the witches' kitchen and giving them their own medicine.
26. The witches are vulnerable to garlic, which is not present in their special soup.
27. The plan works, and the witches turn into monstrous rats.
28. The grandmother and the mice arrive at the Great Witch's room to take all the evil serum.
29. However, the Great Witch drinks the serum and is defeated.
30. The grandmother and the mice leave the Great Witch alone with her cat, which devours her.
31. The grandmother finds information about more witches around the world and decides to travel with her new adopted rodent children to turn them into rats.
32. The grandmother and the mice live happily ever after, playing with miniature attractions and taking care of each other.